Brand/Development name: HyCamp
Company(ies): Alchemia
Principal Therapy Area: Cancer
£195 / $340 / €245
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HA-irinotecan is a proprietary formulation of irinotecan with hyaluronic acid produced with HyACT technology. Through its unique physiochemical and physiological properties, hyaluronic acid provides a means for transporting and targeting anticancer agents to tumours and lymphatic metastases. By combining chemotherapy drugs with hyaluronic acid, their cytotoxic activity is preferentially targeted towards tumour cells and away from normal tissues, thereby effectively increasing the therapeutic index of the drug.
HA-irinotecan produced a statistically-significant increase in PFS (+116 per cent), disease control and the number of cycles of therapy that could be administered to patients in Phase II trials.
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