Brand/Development name: Orplatna
Company(ies): GPC Biotech, Pharmion, Celgene
Principal Therapy Area: Cancer
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Satraplatin is an orally-active third-generation, class IV platinum derivative cancer drug. It binds to the DNA of cancer cells, making the cell incapable of dividing to form new cancer cells, and eventually the cell dies, halting tumour growth.
In August 2008, the EMEA was formally notified by Celgene of Pharmion's (now part of Celgene) decision to withdraw the application for a centralised marketing authorisation for satraplatin 10 and 50mg capsules. The drug was expected to be used, in combination with prednisone and prednisolone, for the treatment of patients with metastatic, hormone-refractory prostate cancer (HRPC) who have failed prior chemotherapy.
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